Off-pump coronary artery bypass grafting is safe and effective in patients with severe left ventricular dysfunction

Authors: Mateo Marin-Cuartas1, Salil V. Deo2, Paulina Ramirez1, Alexander Verevkin1, Sergey Leontyev1, Michael A. Borger1, Piroze M. Davierwala1

Affiliations:

  • 1 University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany, 2 Louis Stokes Cleveland VA Medical Center, Department of Veterans Affairs, Cleveland Ohio, United States of America.

Corresponding Author:

Dr. Piroze M. Davierwala,

University Department of Cardiac Surgery,Heart Center Leipzig,Struempellstrasse 39, 04289 Leipzig, Germany

Email:

Figures presented in the manuscript are recreated and presented here as interactive graphs.

Main Manuscript:

Figure 1.

Figure 2 A:

This figure panel presents the survival (with 95% confidence interval bands) for OPCAB and ONCAB patients in the entire cohort. red = OPCAB , blue = ONCAB.

Figure 2B:

This figure panel presents the survival (with 95% confidence interval bands) for OPCAB and ONCAB patients in the matched groups, calculated using the Kaplan-Meier method. Blue = ONCAB, Red = OPCAB

Supplemental Section

Supplemental Figure 1:

Supplementary figure 1: This figure demonstrates the standardized difference for each co-variate in the propensity score model. The gray dots represent the entire cohort, and the black dots represent the 1:1 matched pairs cohort. After matching, standardized difference for each covariate is between -0.1 and 0.1 demonstrating acceptable model balance. The variable “distance” on the graphic represents the distance between propensity scores for patients. BMI body mass index; CAD coronary artery disease; COPD Chronic obstructive pulmonary disease; ESRD end-stage renal disease; HTN arterial hypertension; LMCA left main coronary artery; LVEF left ventricular ejection fraction; PAD peripheral artery disease; MI myocardial infarction; OHS open heart surgery; PS propensity score.